Buy Cozaar (Losartan Potassium)

Cozaar® (Losartan Potassium) patient handout

• Cozaar (Losartan Potassium) is used to treat hypertension and nephropathy in type 2 diabetic persons.Also Cozaar is used to reduce the risk of stroke in persons with hypertension and left ventricular hypertrophy.

• Cozaar inhibits vasoconstrictive and aldosterone-secreting action of angiotensin II by blocking angiotensin II receptor on the surface of vascular smooth muscle and other tissue cells.
• Therapeutic effects of Cozaar : lowering of blood pressure, slowed progression of diabetic nephropathy, decreased risk of stroke.

• Absorption Absorption describes the process that follows drug administration and its subsequent delivery to systemic circulation. : well absorbed; with extensive first-pass hepatic metabolism, resulting in 33% bioavailability.
• Distribution Drug's distribution in body tissues and fluids. : unknown.
• Metabolism and excretion Important in determining dosage regimens and intervals for persons with hepatic or impaired renal function. : extensive first-pass hepatic metabolism; 14% is converted to an active metabolite.4% of Losartan is excreted unchanged by kidneys; 6% of active metabolite is excreted unchanged by the kidneys with some biliary elimination.
• Half life The half-life of a drug is the amount of time it takes the drug level to decrease by 50% and roughly correlates with the duration of action. : 2 hours.

• Cozaar (Losartan Potassium) is contraindicated in : hypersensitivity, pregnancy, lactation.
• Use Cozaar cautiously in : heart failure, black persons (monotherapy may not be effective), obstructive biliary disorders or hepatic impairment, persons with childbearing potential, children under 18 years.

• Cozaar side effects and adverse reactions (for persons with hypertension or left ventricular hypertrophy) can be : dizziness, asthenia, fatigue, headache, insomnia, edema, chest pain, nasal congestion, sinusitis, pharyngitis, sinus disorder, abdominal pain, nausea, diarrhea, dyspepsia, muscle cramps, myalgia, back or leg pain, cough, upper respiratory infection, angioedema
• Cozaar side efects and adeverse reactions (for persons with nephropathy) can be : asthenia, fatigue, fever, hypesthesia, chest pain, hypotension, orthostatic hypotension, sinusitis, cataract, diarrhea, dyspepsia, gastritis, urinary tract infection, anemia, hyperkalemia, hypoglycemia, weight gain, back pain, leg or knee pain, muscle weakness, cough, bronchitis, cellulitis, flulike syndrome, diabetic vascular disease, angioedema, infection, trauma, diabetic neuropathy.

• Oral administration (adults) : 25 mg / day initially; may be increased as tolerated.
• Oral administration (children over 6 years) : 0.7 mg / kg once daily (up to 1.4 mg / kg or 100 mg / day).

• Continue to take Cozaar (Losartan Potassium) as directed, even if you're feeling well.Take missed doses as soon as remembered if not almost time for next dose; don't double doses.
• Cozaar controls but doesn't cure hypertension.
• Take Cozaar at the same time each day.
• Avoid salt substitutes because these products may contain potassium, which can cause high potassium level in persons taking Cozaar.
• Women : prescriber should be notified immediately if pregnancy is suspected.
• Immediately report swelling of face, eyes, lips or tongue or any breathing difficulty.
• Avoid sunglight or wear sunscreen if you're in sunlight because photosensitivity may occur.
• Excessive perspiration, dehydration, vomiting, diarrhea may lead to fall in blood pressure; consult your prescriber right away if these occur.
• Cozaar may cause dizzines or fainting.Also light-headedness may occur.
• Rise slowly to sitting or standing position to minimize orthostatic hypotension.
• Use contraception while taking Cozaar.