Buy Plavix (Clopidogrel Bisulfate)

Plavix® (Clopidogrel Bisulfate) patient handout

• Plavix (Clopidogrel Bisulfate) is used in the reduction of atherosclerotic events (myocardial infarction, stroke, vascular death) in persons at risk for such events including recent myocardial infarction, acute coronary syndrome (unstable angina/non-Q-wave myocardial infarction), stroke or peripheral vascular disease.

• Plavix inhibits platelet aggregation by irreversibly inhibiting the binding of adenosine triphosphate (ATP) to platelet receptors.
• Therapeutic effects of Plavix : decreased occurrence of atherosclerotic events in patients at risk.

• Absorption Absorption describes the process that follows drug administration and its subsequent delivery to systemic circulation. : well absorbed following oral administration; rapidly metabolized to an active antiplatelet compound.Parent drug has no antiplatelet activity.
• Distribution Drug's distribution in body tissues and fluids. : unknown.
• Protein binding : clopidogrel - 98%; active metabolite - 94%;
• Metabolism and excretion Important in determining dosage regimens and intervals for persons with hepatic or impaired renal function. : rapidly and extensively converted by the liver to its active metabolite, which is then eliminated 50% in urine and 45% in feces.
• Half life The half-life of a drug is the amount of time it takes the drug level to decrease by 50% and roughly correlates with the duration of action. : 8 hours (active metabolite).

• Plavix (Clopidogrel Bisulfate) is strongly contraindicated in : hypersensitivity, pathologic bleeding (peptic ulcer, intracranial hemorrhage), lactation.
• Use Plavix cautiously in : persons at risk for bleeding (trauma, surgery or other pathologic conditions); history of gastrointestinal bleeding/ulcer disease; severe hepatic impairment; pregnancy or children (safety not established yet; use Plavix in pregnancy only if clearly indicated).

• Plavix side effects and adverse reactions can be : depression, dizziness, fatigue, headache, pain, edema, hypertension, epistaxis, rhinitis, hemorrhage, abdominal pain, constipation, diarrhea, dyspepsia, gastritis, ulcers, purpura, arthralgia, bronchitis, coughing, dyspnea, upper respiratory tract infection, rash, pruritus, flulike syndrome.

• Take Plavix (Clopidogrel Bisulfate) exactly as directed.Missed doses should be taken as soon as possible unless almost time for next dose; please don't double doses.
• Notify health care professional promptly if fever, chills, sore throat or unusual bleeding or bruising occurs.
• Notify health care professional of medication regimen prior to treatment or surgery.
• Avoid taking OTC medications containing asipirin or NSAIDs without consulting health care professional.
• It may take longer than usual to stop bleeding.Please refrain from activities in which trauma and bleeding may occur, and you should wear a seatbelt when in a car.
• Inform all health care providers including dentists, before undergoing procedures or starting new drug therapy, that you take Plavix.