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| Protonix is manufactured by : Wyeth Pharmaceuticals |
| Available
forms : Tablets, Injection |
| Generic
name : pantoprazole (pan-toe-pra-zole) |
| Classification
: Therapeutic - antiulcer agents |
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!!! Do not confuse Protonix with Prilosec, Prozac or Prevacid |
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Protonix available forms : |
Tablets (delayed-release) : 20 mg, 40 mg |
Injection : 40 mg per vial. |
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Protonix indications : |
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Protonix action : |
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Protonix binds to an enzyme in the presence of acidic gastric pH, preventing the final transport of hyrdrogen ions into the gastric lumen.
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Therapeutic effects of Protonix : diminished accumulation of acid in the gastric lumen, with lessened acid reflux; healing of duodenal ulcers and esophagitis; decreased acid secretion in hypersecretory conditions.
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Pharmacokinetics for Protonix : |
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Protonix contraindications and precautions : |
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Protonix adverse reactions and side effects : |
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Protonix side effects and adverse reactions can be : headache, abdominal pain, diarrhea, eructation, flatulence, hyperglycemia.
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Protonix dosage : |
Oral administration (adults) :
- GERD : 40 mg of Protonix, once daily.
- Gastric hypersecretory conditions : 40 mg twice daily, up to 120 mg twice daily.
Intravenous (adults) :
- GERD : 40 mg of Protonix, once daily for 7 - 10 days.
- Gastric hypersecretory conditions : 80 mg every 12 hours (up to 240 mg / day).
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How to administer Protonix : |
- Protonix (Pantoprazole Sodium) may be administered with or without food.Don't break, crush or chew tablets.
- Antacids may be used concurrently with Protonix.
- Intravenous : reconstitute each vial with 10 ml of 0.9% NaCl for a concentration of 4 mg/ml.Reconstituted solution is stable for 6 hours at room temperature.
- Direct Intravenous : administer the 4 mg/ml solution undiluted and then administer over at least 2 minutes.
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Useful advices on Protonix : |
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Take Protonix (Pantoprazole Sodium) as directed for the full course of therapy, even if feeling better.
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Avoid alcohol, products containing aspirin or NSAIDs and foods that may cause an increase in gastrointestinal irritation.
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Report onset of black or tarry stools, diarrhea or abdominal pain to health care professional promptly.
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Protonix can be taken without regard to meals.
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Swallow Protonix tablet whole and don't crush, split or chew it.
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Antacids don't affect drug absorption.
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Diabetic persons should know that hypoglycemia may occur.
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Avoid hazardous activities because dizziness may occur.
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Notify prescriber if you're pregnant or if you're planning to become pregnant (don't breastfeed your baby).
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