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Informations about Simvastatin
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What should my health care professional know before I take Simvastatin?
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They need to know if you have any of these conditions:
•an alcohol problem
•any hormone disorder (such as diabetes, under-active thyroid)
•blood salt imbalance
•infection
•kidney disease
•liver disease
•low blood pressure
•muscle disorder ( buy Soma) or
condition
•recent surgery
•seizures (convulsions)
•severe injury
•an unusual or allergic reaction to Simvastatin, other medicines, foods, dyes, or
preservatives
•pregnant or trying to get pregnant
•breast-feeding
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How should I take this medicine?
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Take Simvastatin tablets by mouth. Follow the directions on the prescription label.
Swallow the tablets with a drink of water. If you take the tablets once a day, it is best
to take your dose in the evening hours (like with the evening meal) or at bedtime. You
may take this medicine with or without food. Do not take Simvastatin with grapefruit
juice; orange juice may be used instead. Take your doses at regular intervals. Do not
take your medicine more often than directed.
Contact your pediatrician or health care professional regarding the use of this medicine
in children. Special care may be needed.
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If you miss a dose, take it as soon as you can. If it is almost time for your next dose,
take only that dose. Do not take double or extra doses.
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What drug(s) may interact with Simvastatin?
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Do not take Simvastatin with any of the following:
•amprenavir
•atazanavir
•clarithromycin
•delavirdine
•erythromycin
•grapefruit juice
• indinavir
•itraconazole
•ketoconazole
•lopinavir; ritonavir
•mibefradil
•nefazodone
•nelfinavir
•ritonavir
•saquinavir
•went yeast
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What side effects may I notice from taking Simvastatin?
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Side effects that you should report to your prescriber or health care professional as
soon as possible:
Rare or uncommon:
•dark yellow or brown urine
•decreased urination, difficulty passing urine
•fever ( buy Augmentin)
•muscle pain ( buy Fioricet), tenderness
( buy Butalbital), cramps, or weakness
•redness, blistering, peeling or loosening of the skin, including inside the
mouth
•skin rash ( buy Avita), itching
•unusual tiredness or weakness
•yellowing of the skin or eyes
Side effects that usually do not require medical attention (report to your prescriber or
health care professional if they continue or are bothersome):
•constipation
•headache ( buy Imigran)
•upset stomach ( buy Prilosec),
indigestion, gas, heartburn
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What should I watch for while taking Simvastatin?
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Visit your prescriber or health care professional for regular checks on your progress.
You will need to have regular tests to make sure your liver is working properly.
Tell your prescriber or health care professional as soon as you can if you get any
unexplained muscle pain, tenderness, or weakness, especially if you also have a fever and
tiredness.
Some medicines increase the risk of muscle side effects while taking Simvastatin. Discuss
your drug regimen with your health care provider if you are prescribed certain
antibiotics or antifungals which are not recommended to be taken with Simvastatin
(examples: clarithromycin, erythromycin, itraconazole, ketoconazole). Your prescriber may
decide to temporarily stop taking Simvastatin while you are taking a short course of the
antibiotic or antifungal therapy. Alternatively, your health care provider may prescribe
another antibiotic or antifungal medicine for your condition.
Simvastatin is only part of a total cholesterol-lowering program. Your physician or
dietician can suggest a low-cholesterol and low-fat diet that will reduce your risk of
getting heart and blood vessel disease. Avoid alcohol and smoking, and keep a proper
exercise schedule.
If you are going to have surgery tell your prescriber or health care professional that
you are taking Simvastatin.
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Where can I keep my medicine?
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Keep out of the reach of children in a container that small children cannot open.
Store at room temperature between 5-30 degrees C (41-86 degrees F). Throw away any unused
medicine after the expiration date.
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- additional authority and manufacturer information links about
Simvastatin -
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- from MedlinePlus
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- from Wikipedia.org
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- from MedicineNet.com
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- from eMedicineHealth.com
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- from FDA.gov
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