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Uprima ® click the link above (will open in a new window)
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Uprima ® is used in the treatment of Erectile Dysfunction. ( more info)
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We're sorry, but currently we can't find online pharmacies which sell
genuine Uprima ® manufactured by Abbott
Laboratories.
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Informations about Uprima
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This medicine contains the active ingredient Uprima hydrochloride, which is a type of
medicine known as a dopamine agonist. It works by enhancing the nerve signals that cause
an erection.
An erection is produced via a complex chain of events. The process is started with sexual
stimulation from sight, smell, sound or touch. This causes nerve signals to be sent from
the brain to the penis, which in turn cause the blood vessels in the penis to relax and
widen. This allows the penis to fill with blood and makes it become erect.
Uprima works by enhancing the nerve signals that are sent from the brain to the penis
during sexual stimulation.
It does this by mimicking the action of dopamine, which is a natural chemical called a
neurotransmitter.
Neurotransmitters are involved in sending signals along nerves. They act on special
receptor sites in the nervous system to produce their effects. Dopamine acts on receptors called dopamine
receptors, and this causes nerve signals with various effects to be sent. When dopamine
acts on receptors in an area of the brain called the hypothalamus, it causes the nerve
signals that produce an erection to be sent to the penis.
Uprima mimics the erection-producing effect of dopamine by stimulating the same dopamine
receptors in the hypothalamus. This enhances the effect of natural dopamine that is
produced as a result of sexual stimulation. The nerve signals to the penis are enhanced,
and this results in blood entering the penis, ultimately causing it to become rigid and
erect.
As Uprima enhances the action of dopamine in producing an erection, it will only work
once sexual stimulation has occurred. It does not increase sex-drive ( libido) and is not an aphrodisiac. The
sublingual tablet dissolves under the tongue, where it immediately enters the
bloodstream, causing an erection in most sexually stimulated men in about 20 minutes.
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There should be a minimum of eight hours between doses of this medicine.
You should drink a small amount of water before taking this medicine to help it to
dissolve under the tongue. The tablet should then be placed under the tongue and allowed
to dissolve. If any of the tablet remains after 20 minutes it may be swallowed.
This medicine may uncommonly cause fainting. People normally experience warning symptoms
of this, such as nausea, vomiting, pallor, sweating, hot flushes and dizziness or
lightheadedness. If you experience these symptoms, you should not attempt to stand up -
lie down and raise your legs until the symptoms pass.
This medicine may cause dizziness and lightheadedness. For this reason you should not
drive or operate machinery for at least two hours after taking the medicine, or until any
symptoms pass.
If this medicine is taken with alcohol there is an increased risk of a drop in blood
pressure ( buy Plavix) that might make you feel
dizzy. In addition, alcohol can impair sexual performance.
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Use Uprima with caution in
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Decreased kidney function
Decreased liver function
Elderly people
History of drops in blood pressure when moving from sitting to standing, which causes
dizziness (postural hypotension)
Low blood pressure (hypotension)
Physical abnormality of the penis, such as severe curvature, scarring or Peyronies
disease
Uncontrolled high blood pressure (hypertension)
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Children
Conditions in which sexual activity is not advisable, for example severe heart
disorders
People who have recently had a heart attack
Severe angina not controlled by medical treatment (severe unstable angina)
Severe heart failure
Very low blood pressure ( buy Altace) (severe
hypotension)
Women
This medicine should not be used if you are allergic to one or any of its ingredients.
Please inform your doctor or pharmacist if you have previously experienced such an
allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and
inform your doctor or pharmacist immediately.
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Medicines and their possible side effects can affect individual people in different ways.
The following are some of the side effects that are known to be associated with this
medicine. Because a side effect is stated here, it does not mean that all people using
this medicine will experience that or any side effect.
- headache ( buy Imigran)
- nausea ( buy Amoxicillin)
- sweating
- mouth ulcers
- dizziness
- inflammation of the throat (pharyngitis)
- flushing ( buy Augmentin XR)
- alteration in taste
- yawning
- sleepiness ( buy Rozerem) (somnolence)
- inflammation of the lining of the nose (rhinitis) causing a blocked or runny nose
- cough
- fainting (syncope)
- pain
The side effects listed above may not include all of the side effects reported by the
drugs manufacturer.
For more information about any other possible risks associated with this medicine, please
read the information provided with the medicine or consult your doctor or pharmacist.
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How can Uprima affect other medicines?
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Uprima can be taken by men taking nitrate medications, but the combination may cause
dizziness. Nitrate medications include the following:
- glyceryl trinitrate
- isosorbide mononitrate
- isosorbide dinitrate
- amyl nitrate, also known as poppers.
This medicine can be taken safely with the antisickness medicines domperidone,
ondansetron and prochlorperazine, but other antisickness medicines are not recommended as
they have not yet been studied with this medicine.
This medicine should not be taken with other medicines that affect dopamine activity in
the brain and nervous system (dopamine agonists or antagonists). These medicines include
the following:
- certain treatments for Parkinsons disease, eg
bromocriptine, cabergoline, Uprima, amantadine, levodopa, entacapone, pergolide,
lisuride, pramiprexole, ropinirole, selegiline.
- quinagolide
- antipsychotic medicines.
If this medicine is taken with alcohol there is an increased risk of a drop in blood
pressure. In addition, alcohol can impair sexual performance.
It is recommended that Uprima should not be taken with other treatments for erectile
dysfunction.
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- additional authority and manufacturer information links about Uprima -
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- from DocGuide.com
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- from biopsychiatry.com
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- from PSA-Rising.com
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Related drugs
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Brand versions
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Generic versions
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